Ulcerative
colitis
(UC) is
a
condition,
which
involves
inflammation
and
ulceration
of the
lining
of the
large
intestine,
medically
called
as
colon.
(Colitis=
inflammation
of
colon).
The
digestive
System
is a
system
of
organs
responsible
for
digesting
the food
we eat
so that
nutrients
in the
food are
available
to body
to
provide
required
energy.
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The
digestive
System
consists
of a
long
tube,
which
connects
the
mouth to
the
anus.
Once
food
leaves
the
mouth,
it
enters
the part
of the
GI tract
called
the
esophagus
and then
the
stomach.
In the
stomach
food
pauses
for
sometime
and is
mixed up
with
acid and
juices
present
in the
stomach.
It then
passes
into the
small
intestine,
which
measures
about 20
feet in
length.
The
small
intestine
has
three
parts;
the part
nearest
the
stomach
is the
duodenum,
the next
part is
the
jejunum
and the
third
part
that
connects
to the
large
intestine
is the
ileum.
Small
intestine
is the
site
where
most of
the food
is
digested
with the
assistance
of
secretions
from the
liver,
gall
bladder,
and
pancreas.
The
nutrients
from
this
digested
food are
then
absorbed
through
small
intestine.
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Followed
by the
small
intestine
is the
large
intestine,
which is
more
frequently
referred
to as
the
colon.
The
large
intestine
(colon)
is 6-7
feet in
length.
The
first
part of
the
colon is
called
the
caecum
and the
appendix
is found
there.
The
caecum
and
appendix
are
situated
in right
lower
portion
of the
abdomen.
Large
intestine
then
extends
upward
(this
portion
being
called
as
ascending
colon),
then
takes a
turn and
passes
across
(portion
called
as
transverse
colon)
and then
goes
down
wards
(descending
colon).
At the
end of
descending
colon,
portion
of large
intestine
which
look
like
alphabet
S is
called
as
sigmoid
colon
which
opens
into
rectum.
The main
function
of the
colon is
to
absorb
water
from the
processed
food
residue
that
arrives
after
the
nutrients
have
been
absorbed
in the
small
intestine.
The last
part of
the
colon is
the
rectum,
which is
a
reservoir
for
feces.
Faeces
are
stored
here
until a
bowel
movement
occurs.
The
patients
of
ulcerative
colitis
have
swelling
along
with
ulcers
located
in their
colon
and
rectum.
Broadly
speaking
ulcerative
colitis
is
included
under an
umbrella
term
called
as
inflammatory
bowel
disease
(IBD).
IBD is a
term
referring
to the
diseases
that
cause
chronic
inflammatory
condition
of
digestive
tract.
Another
condition
included
under
this
category
is
Crohns
disease.
Crohn's
disease
can
cause
inflammation
similar
to
ulcerative
colitis
anywhere
in the
digestive
tract
from the
mouth to
the
rectum,
but more
commonly
it
attacks
the
small
intestine
in
contrast
to
ulcerative
colitis,
which
attacks
mainly
the
large
intestine.
Ulcerative
colitis:
Its
types:
The
inflammation
related
to
ulcerative
colitis
usually
occurs
in the
rectum
and
lower
part of
the
colon,
but it
may
affect
the
entire
colon.
Ulcerative
colitis
rarely
affects
the
small
intestine
except
for the
lower
section,
called
the
ileum.
Depending
upon
which
portion
of
intestine
is most
affected
by UC,
it is
put
under
various
types as
follows.
Inflammation
of
Entire
colon
=Pan-colitis
(pan
=entire,
colitis=inflammation
of
colon)
Rectum=
Proctitis
Sigmoid
colon (S
shaped
portion
of colon
located
just
above
the
rectum)
=
Sigmoiditis
Beyond
sigmoid
colon=
Left-sided
colitis
Pathology:
Inside
the
large
intestine,
the
inflammation
of the
inner
lining
(mucosa)
causes
death of
the
colon
lining
cells
and this
results
in sores
or
ulcers.
Also the
inflammation
makes
the
colon to
empty
frequently
resulting
in
diarrhea.
As the
lining
of the
colon is
destroyed,
ulcers
form
releasing
mucus,
pus and
blood.
Nature
of the
disease:
Ulcerative
colitis
is a
chronic
disease
and is
notorious
for its
waxing
and
waning
nature.
Usually
the
patients
of
ulcerative
colitis
have
alternating
periods
of
relative
health
where
the
patient
is
symptom-free
or
experiences
very
mild
symptoms
(remissions)
alternating
with
periods
of
active
disease
(relapse
or
flare).
Fortunately,
as
treatment
has
improved,
the
proportion
of
people
with
continued
symptoms
appears
to have
diminished
significantly.
How
common
is the
condition:
Ulcerative
colitis
is a
global
condition
affecting
people
world
over. It
is
estimated
that in
Unites
states
alone
there
are
about
one
million
people
who
suffer
from
some
form of
IBD.
About
half of
the
people
with IBD
have
ulcerative
colitis;
about
half
have
Crohn's
disease.
Ulcerative
colitis
affects
people
of all
ages,
but at
large it
is the
disease
of young
adults.
Most
cases of
UC are
diagnosed
in
people
between
the ages
15 to 40
years.
However,
children
as small
as few
months
old and
older
people
sometimes
develop
the
disease.
The
incidence
of
Ulcerative
colitis
has
risen
with the
tide of
civilization.
Moreover
this is
a
disease
of young
people
having
grievous
impact
on their
education
and
career.
Ulcerative
colitis
does not
show any
gender
preference
and
affect
males
and
females
equally.
It
appears
to run
in
families.
Studies
also
consistently
conclude
that
ulcerative
colitis
occurs
more
often
within
the
Jewish
population. |